What is Kawasaki disease? | Circulatory System and Disease | NCLEX-RN | Khan Academy

What is Kawasaki disease? | Circulatory System and Disease | NCLEX-RN | Khan Academy


– [Voiceover] Kawasaki disease
is a type of vasculitis that affects medium blood vessels. It was first discovered in Asia by a doctor named Tomisaku Kawasaki. And since then, it’s been noted to affect mostly children of an Asian descent. As I mentioned, it was
first discovered by a doctor by the name of Tomisaku
Kawasaki in January of 1961. With the first diagnosis, he actually had no clue what was going on. But he did note that patients
typically had a fever along with a body rash and rash elsewhere. The rash seemed to affect
the mouth, the eyes, and on the palms and the soles. He also discovered that
some rash was a body rash. When Dr. Kawasaki first saw this disease, he didn’t know what it was. So, he diagnosed fever of unknown origin. This is a blanket term given
when a patient has a fever that is not found to have a diagnosis. However, after encountering
a lot of patients with rash in their mouth, red eyes, maybe on their body and
on their palms and soles, Dr. Kawasaki decided to
publish about this disease. And thus we have the name
Kawasaki disease today. Now, Dr. Kawasaki stated that since the symptoms were so clear cut, he felt that they were pretty close to a discovery of the cause. But unfortunately today,
we actually still don’t understand what causes Kawasaki disease. And the geographic and genetic influences are still really unknown. Now as the years have gone on, Kawasaki disease has
also been given the name mucocutaneous lymph node syndrome. That’s quite a very long description. But it actually really makes sense based off of the findings and symptoms. The word mucocutaneous
refers to mucous membranes. Mucous membranes are wet
surfaces such as the mouth. And cutaneous refers to skin. So for example, skin on your hands or on your feet or on your body. Another mucous membrane
affected is the eyes. Now, where does the word
lymph node come from? Well, commonly in this disease, you can see swelling of nodes in the neck. These are lymph nodes. Specifically, they’re known
as cervical lymph nodes. Cervical means neck. Now, as I mentioned earlier, this is a medium vessel vasculitis. A vasculitis is an
inflammation of blood vessels. And it’s believed to be
caused by the immune system. Though why the immune
system decides to damage the blood vessels in this
disease is really not known. The diagnosis is essentially based off of the clinical symptoms that you see. You can see red eyes, which
is known as conjunctivitis. A more prominent redness of the mouth, this is oral erythema. You may see redness of the
palms and redness of the soles and you may also see a red body rash. So the common theme in
this is rash, red rash. So now if we see some
sort of rash or redness and we also see a fever more than 5 days and a child is less than 5 years old, you should be thinking
about Kawasaki disease. Now, this is actually a disease that’s very important to diagnose early. The reason for that is you can see symptoms affecting the
heart if this disease continues for a longer period of time. Remember, Kawasaki disease
is a vessel disease. Inflammation of blood vessels. So if you see damage to
some of these blood vessels, you can get clots in the
blood vessels of the heart, which causes the heart to
not be able to contract. So maybe it can contract well up here. But down here, it’s not
contracting as effectively. Remember, heart cells need blood. And if they are not getting their blood, they are going to die and
they can’t contract anymore. This cell death of heart cells is called myocardial infarction,
myocardial infarction. This is also known as a heart attack. Along with myocardial infarction, you might have cell death
of the valvular muscles. These are known as the
papillary muscles of the heart. If you cause damage to these, you’re not able to pump blood
effectively out of the heart because the valves are damaged
and not functioning properly. Something more severe
that might be seen is known as pericardial effusion. Pericardial effusion is a collection of blood outside of the heart. This is caused by blood vessel rupture. Blood pours out of the
heart because of a ruptured blood vessel and accumulates
around the heart. This is a very serious
issue and so it makes sense, if you see a kid with
fever who is less than 5 years old and has all these red rashes, you should be very serious about considering Kawasaki disease. Now, since we don’t understand the cause behind Kawasaki disease, using a mnemonic may help
you remember the symptoms. I like to remember a kid on a motor cycle, a Kawasaki motorcycle driving really fast. When he drives really fast, he gets his heart rate
going really quickly. And he drives a motorcycle
using his feet and his hands. And so this may help you remember the rash on the hands and the feet as
well as the heart symptoms. Remember, it’s linked to Kawasaki disease.


61 thoughts on “What is Kawasaki disease? | Circulatory System and Disease | NCLEX-RN | Khan Academy

  1. Omg. I always remembered Kawasaki by the same pnemonic. Thats really the same.
    Child on bike, dtiving fast, so red eyes, hands and feet. Wearing a helmt so cervical LN involved. :

  2. @Little White It's an illness characterized by high fevers, painful rashes, conjunctivitis, dry red mouth, strawberry red tongue, etc. It can also cause heart problems afterwards

  3. @Little White It's an illness characterized by high fevers, painful rashes, conjunctivitis, dry red mouth, strawberry red tongue, etc. It can also cause heart problems afterwards

  4. @Little White It's an illness characterized by high fevers, painful rashes, conjunctivitis, dry red mouth, strawberry re tongue, etc. It can also cause heart problems afterwards

  5. @Little White It's an illness characterized by high fevers, painful rashes, conjunctivitis, dry red mouth, strawberry re tongue, etc. It can also cause heart problems afterwards

  6. I was 10 years old when I had it, my doctors thought it was the German Measles, I was in the hospital for 2 weeks but didn't take the medicine so I could get it again at any point in my life, I am not Asian either

  7. I got Kawasaki disease when I was 4 I live in the uk. With the right treatment I got better in 8 days btw I live in the uk.Their can be side affect for the first 4-5 years as I got chest pains but our doctor told us how to deal with that. I'm now 10 and life has been great

  8. I-have-son-6months-old-diagnosed-for-KAWASAKi…rashes-just-begun-before-the-doc-started-treatment-of-ASPRIN..coz-of-high-fever!..any-support-plzzzzz?

  9. I have a Lil cousin that was diagnose with it at age 4 or 5 I had never heard of it till then. Now they say it comes from Asian decendents and we are African American but who's to say that her father side doesn't have Asian decendents. We all kno that we are amongst the living but who's to say what decendents are in us all. They say only blacks have sickle cells so when we see whites with it it's a well known fact that they have black decendents . Any one with this disease most likely do have Asian decendents because as long as you live you will never kno all your relatives then in the war we mixed it up so beautiful then

  10. My boyfriend had Kawasaki disease when he was seven for about 2 months. But ever since then he's had terrible heart problems and he's been tested for years, but never been properly diagnosed (since they don't know what he has exactly). He'll have random heart pain's that get worse each time they happen and the left part of his back becomes numb. If anyone else has had this please let me know.

  11. my son had this when he was 5,he is now 25. He was hospitalized for two weeks and send to a children's hospital to get treatment..I would never wish this on any child after seeing what my son went through

  12. @Little White I was a baby when I had it, so I don't remember, but that must have sucked to have it at that age.🙁

  13. I'm a Survivor of Kawasaki, but I don't come from an Asian decent, I'm Hispanic, I was diagnosed at age 1 and stopped at age 6, but I still don't know if I have it now or not, all of my family thought I was going to die, but one special doctor was able to help me and now I have rare blood, and the funny thing is my bday is in January😂

  14. I want to thank you for this video and the other videos who have posted about this disease! Your videos were the only videos that truly heloed us. We recently went to the emergency with all of these symptoms with our baby. I've never heard of this disease and Drs don't really explain stuff well. While the Drs in the ER where trying to figure things out and thinking if indeed it was Kawasaki disease, this videos was a true blessing to us. Thank you for taking your time to put this videos together so parents like us who are scare out of our pants in the hospital with our children, have some kind of understanding. Knowing is the first key to our fears, the unknown, and everything that comes with scary diagnosis. God bless you. And Thank you again..

  15. Let me tell you this BTW I'm a 10 year old girl,so before this happens to me I was at the beach in feel like that might have to do something with it I really don't know

  16. Could easily be mistaken for bacterial meningitis except for the nucal rigidity. The rash on the palms is similar to smallpox.

    Infectious diseases are fun

  17. I had this when I was 8. It was so strange and I find it stranger still because I was older than the target age and I’m 100% white. I remember a lot of it and I wish there was more evidence on what causes it, because two of my uncles on both sides had it

  18. Dear doctor or medical student :
    Please do not waste your time with khan academy lectures. They are not for you. But only for non medicals ppl.

  19. Im a survivor. Happened when i was 2 moths old. Maybe even younger. Idk how i got it. Im black, but thats besides the point (sorry if i sounded even remotely racist). My mom says i picked it up from sucking my thumb. They gave me the wrong medicine, and found out i was allergic. Im lucky to be able to even type this comment. Thats why you treat everyone with respect. You never know what will happen to you

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